HDAC3 Antikörper

Produktnummer ABIN7267709

Der Kaninchen-Monoklonal Anti-HDAC3-Antikörper wurde für WB und IP validiert. Er ist geeignet zum Nachweis von HDAC3 in Proben aus Human. }

Kurzübersicht für HDAC3 Antikörper (ABIN7267709)

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser HDAC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-HDAC3 Antikörper

Verwendungszweck: HDAC3 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human HDAC3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HDAC3

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Andere Bezeichnung: HDAC3

Hintergrund: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008],HD3,RPD3,RPD3-2,HDAC3,Apoptosis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,Cell Cycle,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Heart,Heart_Hypertrophy,Immunology & Inflammation,Lipid Metabolism,Lipids,NF-kB Signaling Pathway,Notch Signaling Pathway,Nuclear Receptor Signaling,Signal Transduction,Stem Cells,Tumor suppressors,Wnt/β-Catenin Signaling Pathway,HDAC3

Molekulargewicht: 49kDa

Gen-ID: 8841

UniProt: O15379

Pathways: Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development