FGD1 Antikörper (AA 700-800)
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- Target Alle FGD1 Antikörper anzeigen
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
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Bindungsspezifität
- AA 700-800
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FGD1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Verwendungszweck
- FGD1 Rabbit pAb
- Sequenz
- LLNSTNREDE DTPPNSPNVD LGKRAPTPIR EKEVTMCMRC QEPFNSITKR RHHCKACGHV VCGKCSEFRA RLVYDNNRSN RVCTDCYVAL HGVPGSSPAC S
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2).
- Isotyp
- IgG
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
- Andere Bezeichnung
- FGD1 (FGD1 Produkte)
- Hintergrund
- This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.,FGD1,AAS,FGDY,MRXS16,ZFYVE3,FYVE,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,FGD1
- Molekulargewicht
- 106kDa
- Gen-ID
- 2245
- UniProt
- P98174
- Pathways
- Neurotrophin Signalübertragung
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