FANCD2 Antikörper

Produktnummer ABIN7267126

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch FANCD2 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FANCD2 Antikörper (ABIN7267126)

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FANCD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FANCD2 Antikörper

Verwendungszweck: FANCD2 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human FANCD2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FANCD2

Target: FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Andere Bezeichnung: FANCD2

Hintergrund: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],FA4,FAD,FACD,FAD2,FA-D2,FANCD,FANCD2,Cell Biology & Developmental Biology,Cell Cycle,DNA Damage & Repair,Epigenetics & Nuclear Signaling,G2/M DNA Damage Checkpoint,FANCD2

Molekulargewicht: 166kDa

Gen-ID: 2177

UniProt: Q9BXW9

Pathways: DNA Reparatur