EGFR Antikörper (pTyr1173)

Produktnummer ABIN7266989

Der Kaninchen Monoklonal Anti-EGFR-Antikörper wurde für WB validiert. Er ist geeignet, EGFR in Proben von Human zu detektieren.

Kurzübersicht für EGFR Antikörper (pTyr1173) (ABIN7266989)

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EGFR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EGFR Antikörper

Bindungsspezifität: pTyr1173

Verwendungszweck: Phospho-EGFR-Y1173 Rabbit mAb

Kreuzreaktivität: Human

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding Y1173 of human EGFR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EGFR

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Andere Bezeichnung: EGFR

Hintergrund: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],ERBB, ERBB1, HER1, NISBD2, PIG61, mENA,Angiogenesis,Cancer,Cardiovascular,Cell Biology & Developmental Biology,ErbB-HER Signaling Pathway,G protein signaling,Growth factors,Growth factors_EGF,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Kinase,Kinase_Tyrosine kinases,Phospholipase Signaling Pathway,Protein phosphorylation,Signal Transduction,Tumor biomarkers,EGFR

Molekulargewicht: 175kDa

Gen-ID: 1956

UniProt: P00533

Pathways: NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine