DDR1 Antikörper (pTyr792)

Produktnummer ABIN7266789

Dieses Anti-DDR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DDR1 in WB. Geeignet für Human.

Kurzübersicht für DDR1 Antikörper (pTyr792) (ABIN7266789)

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DDR1 Antikörper

Bindungsspezifität: pTyr792

Verwendungszweck: Phospho-DDR1-Y792 Rabbit pAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A phospho synthetic peptide corresponding to residues surrounding Y792 of human DDR1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DDR1

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Andere Bezeichnung: DDR1

Hintergrund: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011],CAK,CD167,DDR,EDDR1,HGK2,MCK10,NEP,NTRK4,PTK3,PTK3A,RTK6,TRKE,DDR1,Cancer,Cardiovascular,CDs,Heart,Heart_Cardiogenesis,Immunology & Inflammation,Kinase,Kinase_Tyrosine kinases,Neuroscience,Protein phosphorylation,Signal Transduction,DDR1

Molekulargewicht: 27kDa/97kDa/99kDa/101kDa

Gen-ID: 780

UniProt: Q08345

Pathways: RTK Signalweg, Smooth Muscle Cell Migration