Cullin 1 Antikörper
Kurzübersicht für Cullin 1 Antikörper (ABIN7266541)
Target
Alle Cullin 1 (CUL1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Cullin 1 Rabbit mAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human Cullin 1
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cullin 1 (CUL1)
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Andere Bezeichnung
- CUL1
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Hintergrund
- The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases. Humans express seven cullin proeins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.,Cullin 1,CUL1,cullin-1,MGC149834,MGC149835,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cell cycle inhibitors,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,CUL1
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Molekulargewicht
- 90kDa
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Gen-ID
- 8454
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UniProt
- Q13616
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Pathways
- Zellzyklus, Hedgehog Signalweg, Mitotic G1-G1/S Phases, Regulation of Cell Size
Target
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