CD276 Antikörper (AA 100-200)

Produktnummer ABIN7266182

Der Kaninchen Polyklonal Anti-CD276-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, CD276 in Proben von Human zu detektieren.

Kurzübersicht für CD276 Antikörper (AA 100-200) (ABIN7266182)

Target: CD276

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD276 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CD276 Antikörper

Bindungsspezifität: AA 100-200

Verwendungszweck: B7-H3/CD276 Rabbit pAb

Sequenz: LAQGNASLRL QRVRVADEGS FTCFVSIRDF GSAAVSLQVA APYSKPSMTL EPNKDLRPGD TVTITCSSYQ GYPEAEVFWQ DGQGVPLTGN VTTSQMANEQ G

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human B7-H3/CD276 (NP_001019907.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000
IHC-P, 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CD276

Target: CD276

Andere Bezeichnung: CD276

Hintergrund: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CD276;4Ig-B7-H3;B7-H3;B7H3;B7RP-2,Cancer,Tumor biomarkers,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CD276

Molekulargewicht: 33kDa/52kDa/57kDa

Gen-ID: 80381

UniProt: Q5ZPR3

Pathways: Cancer Immune Checkpoints