Rekombinanter CD276 Antikörper (Extracellular Domain)

Produktnummer ABIN7072434

Der Kaninchen Chimeric anti-CD276 Antikörper (Klon MJ18) (ABIN7072434) detektiert spezifisch CD276 in FACS und BR. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Rekombinanter CD276 Antikörper (Extracellular Domain) (ABIN7072434)

Target: CD276

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser CD276 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Blocking Reagent (BR)

Klon: MJ18

Produktdetails anti-CD276 Antikörper

Bindungsspezifität: AA 1-242, Extracellular Domain

Verwendungszweck: Anti-B7-H3 [MJ18], Rabbit IgG, kappa

Spezifität:

This antibody binds to mouse B7-H3 and does not react with other B7-family molecules.

Application Notes original Clone: This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.

Produktmerkmale: This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1-242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

OriginalSpeciesName: Rat

OriginalFormat: IgG1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD276

Target: CD276

Andere Bezeichnung: B7-H3

Hintergrund: CD276, B7H3

UniProt: Q8VE98

Pathways: Cancer Immune Checkpoints