BIRC2 Antikörper

Produktnummer ABIN7265820

Produktdetails anti-BIRC2 Antikörper

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser BIRC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: cIAP1 Rabbit mAb

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human cIAP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu BIRC2

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Andere Bezeichnung: BIRC2 (BIRC2 Produkte)

Hintergrund: The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],API1,HIAP2,Hiap-2,MIHB,RNF48,c-IAP1,cIAP1,BIRC2,Apoptosis,Apoptosis_Caspases,Apoptosis_Death receptors & ligands,Apoptosis_Inhibition of Apoptosis,Cancer,Cell Biology & Developmental Biology,Death Receptor Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,Invasion and Metastasis,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,BIRC2

Molekulargewicht: 70kDa

Gen-ID: 329

UniProt: Q13490

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades