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ALDH2 Antikörper

ALDH2 Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7265538
  • Target Alle ALDH2 Antikörper anzeigen
    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
    Reaktivität
    • 59
    • 23
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    • 10
    • 2
    Kaninchen
    Klonalität
    • 44
    • 15
    Monoklonal
    Konjugat
    • 34
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ALDH2 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 28
    • 22
    • 10
    • 9
    • 9
    • 5
    • 3
    • 1
    Western Blotting (WB)
    Verwendungszweck
    ALDH2 Rabbit mAb
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Monoclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthesized peptide derived from human ALDH2
    Isotyp
    IgG
    Top Product
    Discover our top product ALDH2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
    Andere Bezeichnung
    ALDH2 (ALDH2 Produkte)
    Hintergrund
    This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016],ALDH-E2, ALDHI, ALDM,Cancer,Cardiovascular,Endocrine & Metabolism,Heart,Heart_Cardiac metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Signal Transduction,ALDH2
    Molekulargewicht
    56kDa
    Gen-ID
    217
    UniProt
    P05091
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