GIT1 Antikörper (C-Term)

Produktnummer ABIN7233038

Der Maus Monoklonal Anti-GIT1-Antikörper wurde für WB, IP und IF/ICC validiert. Er ist geeignet, GIT1 in Proben von Ratte zu detektieren.

Kurzübersicht für GIT1 Antikörper (C-Term) (ABIN7233038)

Target: GIT1

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GIT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)

Klon: S39B-8

Produktdetails anti-GIT1 Antikörper

Bindungsspezifität: AA 375-770, C-Term

Verwendungszweck: Anti-GIT1 Mouse Monoclonal Antibody

Spezifität: This antibody recognizes human, mouse and rat GIT1. It does not cross-react with GIT2.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein G affinity chromatography.

Immunogen: Fusion protein corresponding to aa 375-770 (C-terminus) of rat GIT1 (accession no.Q9Z272).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoblotting: use at 1 μg/mL. Predicted molecular weight is ~90 kDa.
Positive control: rat brain lysate.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: This antibody is stable for at least one (1) year at -20°C.

Details zu GIT1

Target: GIT1

Andere Bezeichnung: Git1

Hintergrund: ARF GTPase-activating protein GIT1,G-protein coupled receptor (GPCR) kinase interacting proteins 1 and 2 (GIT1 and GIT2) are highly conserved ubiquitous scaffold proteins involved in localized signaling to help regulate focal contact assembly and cytoskeletal dynamics. GIT proteins contain multiple interaction domains for small GTPases, kinases, the Rho family GEF PIX, and the focal adhesion protein paxillin. GIT1 is localized to focal adhesions, cyto- plasmic complexes and membrane protrusions, and it regulates cell protrusion formation and cell migration.

UniProt: Q9Z272