GIT1 Antikörper (AA 487-517)
Kurzübersicht für GIT1 Antikörper (AA 487-517) (ABIN391615)
Target
Alle GIT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 487-517
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Homologie
- M, Rat
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from human GIT1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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: "The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation." in: American journal of physiology. Cell physiology, Vol. 305, Issue 5, pp. C519-28, (2013) (PubMed).
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- GIT1
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Andere Bezeichnung
- GIT1
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Hintergrund
- GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
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Molekulargewicht
- 84341
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Gen-ID
- 28964
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NCBI Accession
- NP_001078923, NP_054749
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UniProt
- Q9Y2X7
Target
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