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ZYX Antikörper (pSer142)

Der Kaninchen Polyklonal Anti-ZYX Antikörper wurde für WB und ELISA validiert. Er ist geeignet, ZYX in Proben von Human zu detektieren.
Produktnummer ABIN7225018

Kurzübersicht für ZYX Antikörper (pSer142) (ABIN7225018)

Target

Alle ZYX Antikörper anzeigen
ZYX (Zyxin (ZYX))

Reaktivität

  • 72
  • 34
  • 17
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 60
  • 11
  • 1
Kaninchen

Klonalität

  • 44
  • 27
Polyklonal

Konjugat

  • 36
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
Dieser ZYX Antikörper ist unkonjugiert

Applikation

  • 50
  • 25
  • 23
  • 20
  • 18
  • 13
  • 11
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer142

    Verwendungszweck

    Zyxin (phospho Ser142) Polyclonal Antibody

    Spezifität

    Phospho-Zyxin (S142) Polyclonal Antibody detects endogenous levels of Zyxin protein only when phosphorylated at S142.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    Immunogen

    Synthesized peptide derived from human Zyxin Phospho-Ser142

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

    Kommentare

    Primary Antibody

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Target

    ZYX (Zyxin (ZYX))

    Andere Bezeichnung

    Zyxin

    Hintergrund

    Rabbit Anti-Zyxin (phospho Ser142) Polyclonal Antibody,ZYX, Zyxin, Zyxin-2,Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.,Zyxin

    Molekulargewicht

    observerd band 61kDa

    Gen-ID

    7791

    UniProt

    Q15942
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