SMAD3 Antikörper (pSer213)

Produktnummer ABIN7231398

Der Kaninchen Polyklonal Anti-SMAD3 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, SMAD3 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SMAD3 Antikörper (pSer213) (ABIN7231398)

Target: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMAD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SMAD3 Antikörper

Bindungsspezifität: pSer213

Verwendungszweck: Smad3 (Phospho-Ser213) Polyclonal Antibody

Spezifität: This antibody detects endogenous levels of Smad3 when Phospho occurs at Ser213

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human Smad3 (Phospho-Ser213) Antibody protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu SMAD3

Target: SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))

Andere Bezeichnung: Smad3

Hintergrund: Rabbit Anti-Smad3 (Phospho-Ser213) Polyclonal Antibody,Mothers against decapentaplegic homolog 3, MAD homolog 3, Mad3, Mothers against DPP homolog 3, hMAD-3, JV15-2, SMAD family member 3, SMAD 3, Smad3, hSMAD3,SMAD3 (SMAD Family Member 3) is a Protein Coding gene. Diseases associated with SMAD3 include Loeys-Dietz Syndrome 3 and Smad3-Related Loeys-Dietz Syndrome. Among its related pathways are Transcription Androgen Receptor nuclear signaling and AGE/RAGE pathway. The protein encoded by SMAD3 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene' mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.,Smad3

Molekulargewicht: observerd band 50kDa

Gen-ID: 4088

UniProt: P84022

Pathways: Zellzyklus, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagie