SCO2 Antikörper (AA 181-230)

Produktnummer ABIN7231290

Der Kaninchen Polyklonal anti-SCO2 Antikörper (ABIN7231290) detektiert spezifisch SCO2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für SCO2 Antikörper (AA 181-230) (ABIN7231290)

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SCO2 Antikörper

Bindungsspezifität: AA 181-230

Verwendungszweck: Rabbit Anti-SCO2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of SCO2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SCO2 protein at AA range: 181-230

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SCO2

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Andere Bezeichnung: SCO2

Hintergrund: Protein SCO2 homolog, mitochondrialCytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors, SCO2 encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in SCO2 are associated with fatal infantile encephalocardiomyopathy and myopia 6.

Molekulargewicht: 29kD

Gen-ID: 9997

UniProt: O43819

Pathways: Transition Metal Ion Homeostasis, Warburg Effekt