PTPN12 Antikörper

Produktnummer ABIN7230828

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch PTPN12 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für PTPN12 Antikörper (ABIN7230828)

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPN12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PTPN12 Antikörper

Verwendungszweck: PTN12 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PTN12 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PTN12 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PTPN12

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Andere Bezeichnung: PTN12

Hintergrund: Rabbit Anti-PTN12 Polyclonal Antibody,Tyrosine-protein phosphatase non-receptor type 12, PTP-PEST, Protein-tyrosine phosphatase G1, PTPG1,PTPN12 (Protein Tyrosine Phosphatase, Non-Receptor Type 12) is a Protein Coding gene. Diseases associated with PTPN12 include Colorectal Cancer and Colonic Benign Neoplasm. Among its related pathways are DNA Damage and Signaling by ERBB2. The protein encoded by PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility.,PTN12

Molekulargewicht: observerd band 85kDa

Gen-ID: 5782

UniProt: Q05209