PPP1R13B Antikörper (AA 630-680)

Produktnummer ABIN7227388

Dieser Anti-PPP1R13B Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von PPP1R13B in ELISA und IHC (p). Geeignet für Human.

Kurzübersicht für PPP1R13B Antikörper (AA 630-680) (ABIN7227388)

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R13B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PPP1R13B Antikörper

Bindungsspezifität: AA 630-680

Verwendungszweck: ASPP1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of ASPP1

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ASPP1 protein at AA range: 630-680

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PPP1R13B

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Andere Bezeichnung: ASPP1

Hintergrund: Rabbit Anti-ASPP1 Polyclonal Antibody,Apoptosis-stimulating of p53 protein 1, Protein phosphatase 1 regulatory subunit 13B,PPP1R13B encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. PPP1R13B (Protein Phosphatase 1 Regulatory Subunit 13B) is a Protein Coding gene. Among its related pathways are Activation of BH3-only proteins and TP53 Regulates Transcription of Cell Death Genes.,ASPP1

Gen-ID: 23368

UniProt: Q96KQ4

Pathways: p53 Signalweg