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PPP1R13B Antikörper (Middle Region)

PPP1R13B Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783179
  • Target Alle PPP1R13B Antikörper anzeigen
    PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 51
    • 12
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)
    Wirt
    • 51
    • 1
    Kaninchen
    Klonalität
    • 51
    • 1
    Polyklonal
    Konjugat
    • 17
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PPP1R13B Antikörper ist unkonjugiert
    Applikation
    • 38
    • 25
    • 13
    • 13
    • 3
    • 3
    • 3
    • 3
    Western Blotting (WB)
    Sequenz
    EFDLVQRIIY EVEDPSKPND EGITPLHNAV CAGHHHIVKF LLDFGVNVNA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PPP1R13B. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PPP1R13B
    Top Product
    Discover our top product PPP1R13B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1090 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
    Andere Bezeichnung
    PPP1R13B (PPP1R13B Produkte)
    Synonyme
    ASPP1 antikoerper, p53BP2-like antikoerper, p85 antikoerper, AI449786 antikoerper, AW545810 antikoerper, Tp53bp2 antikoerper, Trp53bp2 antikoerper, protein phosphatase 1 regulatory subunit 13B antikoerper, protein phosphatase 1, regulatory subunit 13B antikoerper, protein phosphatase 1 regulatory subunit 13B L homeolog antikoerper, protein phosphatase 1, regulatory subunit 13Bb antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 13B antikoerper, PPP1R13B antikoerper, Ppp1r13b antikoerper, ppp1r13b.L antikoerper, ppp1r13bb antikoerper, ppp1r13b antikoerper
    Hintergrund
    PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
    Alias Symbols: ASPP1, KIAA0771, p53BP2-like, p85
    Protein Interaction Partner: TRAF1, CCDC184, MIPOL1, LATS2, SIAH2, PPP1CC, PPP1CA, HRAS, LATS1, KHDRBS1, ERBB2, CEP63, TNIK, CDC5L, UBC, PLEKHA5, APC, TP63, TP73, E2F4, E2F3, E2F2, E2F1,
    Protein Size: 1090
    Molekulargewicht
    119 kDa
    Gen-ID
    23368
    NCBI Accession
    NM_015316, NP_056131
    UniProt
    Q96KQ4
    Pathways
    p53 Signalweg
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