POLD4 Antikörper

Produktnummer ABIN7228276

Der Kaninchen Polyklonal anti-POLD4 Antikörper wird verwendet zum Nachweis von POLD4 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für POLD4 Antikörper (ABIN7228276)

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-POLD4 Antikörper

Verwendungszweck: Rabbit Anti-DPOD4 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of DPOD4 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DPOD4 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu POLD4

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Andere Bezeichnung: DPOD4

Hintergrund: DNA polymerase delta subunit 4, DNA polymerase delta subunit p12POLD4 (DNA Polymerase Delta 4, Accessory Subunit) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Telomere C-strand (Lagging Strand) Synthesis. POLD4 encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein.

Molekulargewicht: 11kD

Gen-ID: 57804

UniProt: Q9HCU8

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA