POLB Antikörper (AA 270-350)

Produktnummer ABIN7214594

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch POLB in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für POLB Antikörper (AA 270-350) (ABIN7214594)

Target: POLB (Polymerase (DNA Directed), beta (POLB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-POLB Antikörper

Bindungsspezifität: AA 270-350

Verwendungszweck: Rabbit Anti-DNA pol β Polyclonal Antibody

Spezifität: DNA pol β Polyclonal Antibody detects endogenous levels of DNA pol β protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human DNA pol beta at AA range: 270-350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu POLB

Target: POLB (Polymerase (DNA Directed), beta (POLB))

Andere Bezeichnung: DNA pol beta

Hintergrund: POLB, DNA polymerase betaDNA polymerase beta encoded by POLB is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of POLB exist, but the full-length nature of only one has been described to date.

Molekulargewicht: 38kD

Gen-ID: 5423

UniProt: P06746

Pathways: DNA Reparatur