PI3K p101 Antikörper (AA 670-750)

Produktnummer ABIN7220738

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PI3K p101 in ELISA, IHC, WB und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für PI3K p101 Antikörper (AA 670-750) (ABIN7220738)

Target: PI3K p101 (Phosphoinositide 3 Kinase, p101 (PI3K p101))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PI3K p101 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-PI3K p101 Antikörper

Bindungsspezifität: AA 670-750

Verwendungszweck: Rabbit Anti-PI 3-kinase p101 Polyclonal Antibody

Spezifität: PI 3-kinase p101 Polyclonal Antibody detects endogenous levels of PI 3-kinase p101 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human PI 3-kinase p101 at AA range: 670-750

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PI3K p101

Target: PI3K p101 (Phosphoinositide 3 Kinase, p101 (PI3K p101))

Andere Bezeichnung: PI 3-kinase p101

Hintergrund: PIK3R5, Phosphoinositide 3-kinase regulatory subunit 5, PI3-kinase regulatory subunit 5, PI3-kinase p101 subunit, Phosphatidylinositol 4, 5-bisphosphate 3-kinase regulatory subunit, PtdIns-3-kinase regulatory subunit, Protein FOAP-2, PtdIns-Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: i, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.

Molekulargewicht: 100kD

Gen-ID: 23533

UniProt: Q8WYR1