NCOR1 Antikörper (AA 30-110)

Produktnummer ABIN7226046

Der Kaninchen Polyklonal anti-NCOR1 Antikörper (ABIN7226046) detektiert spezifisch NCOR1 in ELISA, WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für NCOR1 Antikörper (AA 30-110) (ABIN7226046)

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOR1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NCOR1 Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: N-CoR Polyclonal Antibody

Spezifität: N-CoR Polyclonal Antibody detects endogenous levels of N-CoR protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human N-CoR at AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu NCOR1

Target: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Andere Bezeichnung: N-CoR

Hintergrund: Rabbit Anti-N-CoR Polyclonal Antibody,NCOR1, KIAA1047, Nuclear receptor corepressor 1, N-CoR, N-CoR1,NCOR1 (nuclear receptor corepressor 1) encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. NCOR1 is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of NCOR1 are found on chromosomes 17 and 20.,Nuclear receptor corepressor 1

Molekulargewicht: observerd band 270kDa

Gen-ID: 9611

UniProt: O75376

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process