Neuregulin 4 Antikörper (AA 11-60)

Produktnummer ABIN7230132

Der Kaninchen Polyklonal anti-Neuregulin 4 Antikörper wird verwendet zum Nachweis von Neuregulin 4 in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Neuregulin 4 Antikörper (AA 11-60) (ABIN7230132)

Target: Neuregulin 4 (NRG4)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuregulin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Neuregulin 4 Antikörper

Bindungsspezifität: AA 11-60

Verwendungszweck: Rabbit Anti-NRG4 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of NRG4 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NRG4 protein at AA range: 11-60

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Neuregulin 4

Target: Neuregulin 4 (NRG4)

Andere Bezeichnung: NRG4

Hintergrund: Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4NRG4 (Neuregulin 4) is a Protein Coding gene. Among its related pathways are RET signaling and Signaling by ERBB2. GO annotations related to this gene include receptor binding and growth factor activity. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity).

Molekulargewicht: 12kD

Gen-ID: 145957

UniProt: Q8WWG1

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung