NADPH Oxidase 4 Antikörper

Produktnummer ABIN7230064

Dieser Anti-NADPH Oxidase 4 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von NADPH Oxidase 4 in WB und ELISA. Geeignet für Human, Ratte und Maus.

Kurzübersicht für NADPH Oxidase 4 Antikörper (ABIN7230064)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NADPH Oxidase 4 Antikörper

Verwendungszweck: NOX4 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of NOX4 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human NOX4 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NOX4

Hintergrund: Rabbit Anti-NOX4 Polyclonal Antibody,NADPH oxidase 4, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase,NOX4 gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.,NOX4

Molekulargewicht: observerd band 63kDa

Gen-ID: 50507

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration