MYCN Antikörper

Produktnummer ABIN7229818

Der Kaninchen Polyklonal anti-MYCN Antikörper wird verwendet zum Nachweis von MYCN in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für MYCN Antikörper (ABIN7229818)

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYCN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MYCN Antikörper

Verwendungszweck: Rabbit Anti-MYCN Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MYCN protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MYCN protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Andere Bezeichnung: MYCN

Hintergrund: N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37, bHLHe37MYCN gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 51kD

Gen-ID: 4613

UniProt: P04198