MLL2 Antikörper (AA 1430-1510)

Produktnummer ABIN7229696

Der Kaninchen-Polyklonal Anti-MLL2-Antikörper wurde für IHC (p) validiert. Er ist geeignet zum Nachweis von MLL2 in Proben aus Human. }

Kurzübersicht für MLL2 Antikörper (AA 1430-1510) (ABIN7229696)

Target: MLL2 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLL2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MLL2 Antikörper

Bindungsspezifität: AA 1430-1510

Verwendungszweck: MLL2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MLL2 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MLL2 protein at AA range: 1430-1510

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MLL2

Target: MLL2 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2))

Andere Bezeichnung: MLL2

Hintergrund: Rabbit Anti-MLL2 Polyclonal Antibody,Histone-lysine N-methyltransferase 2D, Lysine N-methyltransferase 2D, ALL1-related protein, Myeloid/lymphoid or mixed-lineage leukemia protein 2,KMT2D (Lysine Methyltransferase 2D) is a Protein Coding gene. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Chromatin organization. The protein encoded by KMT2D is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in KMT2D have been shown to be a cause of Kabuki syndrome.,MLL2

Molekulargewicht: observerd band 609kDa

Gen-ID: 8085

UniProt: O14686

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effekt