MLH1 Antikörper (AA 410-490)

Produktnummer ABIN7215772

Dieser Anti-MLH1-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von MLH1 in WB, ELISA und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für MLH1 Antikörper (AA 410-490) (ABIN7215772)

Target: MLH1 (MutL Homolog 1 (MLH1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-MLH1 Antikörper

Bindungsspezifität: AA 410-490

Verwendungszweck: MLH1 Polyclonal Antibody

Spezifität: MLH1 Polyclonal Antibody detects endogenous levels of MLH1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human MLH1 at AA range: 410-490

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MLH1

Target: MLH1 (MutL Homolog 1 (MLH1))

Andere Bezeichnung: MLH1

Hintergrund: Rabbit Anti-MLH1 Polyclonal Antibody,MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1,MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E.coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.,DNA mismatch repair protein Mlh1

Molekulargewicht: observerd band 85kDa

Gen-ID: 4292

UniProt: P40692

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response