MAP3K11 Antikörper (pSer674)

Produktnummer ABIN7213356

Der Kaninchen Polyklonal Anti-MAP3K11 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, MAP3K11 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für MAP3K11 Antikörper (pSer674) (ABIN7213356)

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MAP3K11 Antikörper

Bindungsspezifität: pSer674

Verwendungszweck: MLK3 (phospho Ser674) Polyclonal Antibody

Spezifität: Phospho-MLK3 (S674) Polyclonal Antibody detects endogenous levels of MLK3 protein only when phosphorylated at S674.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human MLK3 Phospho-Ser674

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MAP3K11

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Andere Bezeichnung: MLK3

Hintergrund: Rabbit Anti-MLK3 (phospho Ser674) Polyclonal Antibody,MAP3K11, MLK3, PTK1, SPRK, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase,Mitogen-activated protein kinase 11 encoded by MAP3K11 is a member of the serine/threonine kinase family. Mitogen-activated protein kinase 11 contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.,Mitogen-activated protein kinase kinase kinase 11

Gen-ID: 4296

UniProt: Q16584

Pathways: MAPK Signalweg, Interferon-gamma Pathway