MRGPRD Antikörper

Produktnummer ABIN7229754

Der Kaninchen Polyklonal anti-MRGPRD Antikörper (ABIN7229754) detektiert spezifisch MRGPRD in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MRGPRD Antikörper (ABIN7229754)

Target: MRGPRD (MAS-Related GPR, Member D (MRGPRD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGPRD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MRGPRD Antikörper

Verwendungszweck: MRGRD Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MRGRD protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MRGRD protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MRGPRD

Target: MRGPRD (MAS-Related GPR, Member D (MRGPRD))

Andere Bezeichnung: MRGRD

Hintergrund: Rabbit Anti-MRGRD Polyclonal Antibody,Mas-related G-protein coupled receptor member D, Beta-alanine receptor, G-protein coupled receptor TGR7,MRGPRD (MAS Related GPR Family Member D) is a Protein Coding gene. Among its related pathways are ACE Inhibitor Pathway, Pharmacodynamics. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).,MRGRD

Molekulargewicht: observerd band 35kDa

Gen-ID: 116512

UniProt: Q8TDS7