IL15RA Antikörper (AA 70-150)

Produktnummer ABIN7221810

Der Kaninchen Polyklonal anti-IL15RA Antikörper (ABIN7221810) detektiert spezifisch IL15RA in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.

Kurzübersicht für IL15RA Antikörper (AA 70-150) (ABIN7221810)

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL15RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL15RA Antikörper

Bindungsspezifität: AA 70-150

Verwendungszweck: Rabbit Anti-IL-15Rα Polyclonal Antibody

Spezifität: IL-15Rα Polyclonal Antibody detects endogenous levels of IL-15Rα protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human IL-15Ralpha at AA range: 70-150

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Andere Bezeichnung: IL-15Ralpha

Hintergrund: IL15RA, Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, CD antigen CD215IL15RA encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

Molekulargewicht: 32kD

Gen-ID: 3601

UniProt: Q13261

Pathways: JAK-STAT Signalweg