IL15RA Antikörper (AA 79-106)

Produktnummer ABIN1538627

Der Kaninchen Polyklonal anti-IL15RA Antikörper wird verwendet zum Nachweis von IL15RA in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für IL15RA Antikörper (AA 79-106) (ABIN1538627)

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL15RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39373

Produktdetails anti-IL15RA Antikörper

Bindungsspezifität: AA 79-106

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL15RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-106 amino acids from the Central region of human IL15RA.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: IL15RA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Andere Bezeichnung: IL15RA

Hintergrund: This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

Molekulargewicht: 28233

Gen-ID: 3601

NCBI Accession: NP_001230468, NP_001243694, NP_002180, NP_751950

UniProt: Q13261

Pathways: JAK-STAT Signalweg