IGF1R Antikörper (pTyr1161)

Produktnummer ABIN7229070

Dieser Anti-IGF1R-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von IGF1R in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für IGF1R Antikörper (pTyr1161) (ABIN7229070)

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGF1R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IGF1R Antikörper

Bindungsspezifität: pTyr1161

Verwendungszweck: IGF1R (Phospho-Tyr1161) Polyclonal Antibody

Spezifität: This antibody detects endogenous levels of IGF1R when Phospho occurs at Tyr1161

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human IGF1R (Phospho-Tyr1161) Antibody protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu IGF1R

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Andere Bezeichnung: IGF1R

Hintergrund: Rabbit Anti-IGF1R (Phospho-Tyr1161) Polyclonal Antibody,Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I receptor, CD antigen CD221,IGF1R (Insulin Like Growth Factor 1 Receptor) is a Protein Coding gene. Diseases associated with IGF1R include Insulin-Like Growth Factor I and Leprechaunism. Among its related pathways are Transcription Androgen Receptor nuclear signaling and p70S6K Signaling. This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for IGF1Re.,IGF1R

Molekulargewicht: observerd band 155kDa

Gen-ID: 3480

UniProt: P08069

Pathways: RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie