HMGB2 Antikörper (AA 100-180)

Produktnummer ABIN7215282

Der Kaninchen Polyklonal Anti-HMGB2 Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, HMGB2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für HMGB2 Antikörper (AA 100-180) (ABIN7215282)

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HMGB2 Antikörper

Bindungsspezifität: AA 100-180

Verwendungszweck: HMG-2 Polyclonal Antibody

Spezifität: HMG-2 Polyclonal Antibody detects endogenous levels of HMG-2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human HMG-2 at AA range: 100-180

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu HMGB2

Target: HMGB2 (High Mobility Group Box 2 (HMGB2))

Andere Bezeichnung: HMG-2

Hintergrund: Rabbit Anti-HMG-2 Polyclonal Antibody,HMGB2, HMG2, High mobility group protein B2, High mobility group protein 2, HMG-2,HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that high mobility group protein B2 is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.,High mobility group protein B2

Molekulargewicht: observerd band 27kDa

Gen-ID: 3148

UniProt: P26583

Pathways: Cellular Response to Molecule of Bacterial Origin