Glutamate Receptor 1 Antikörper (pSer863)

Produktnummer ABIN7221294

Dieser Anti-Glutamate Receptor 1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Glutamate Receptor 1 in WB, ELISA und IHC (p). Geeignet für Human, Ratte und Maus.

Kurzübersicht für Glutamate Receptor 1 Antikörper (pSer863) (ABIN7221294)

Target: Glutamate Receptor 1 (GLUR1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Glutamate Receptor 1 Antikörper

Bindungsspezifität: pSer863

Verwendungszweck: GluR-1 (phospho Ser863) Polyclonal Antibody

Spezifität: Phospho-GluR-1 (S863) Polyclonal Antibody detects endogenous levels of GluR-1 protein only when phosphorylated at S863.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human GluR-1 Phospho-Ser863

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Andere Bezeichnung: GluR-1

Hintergrund: Rabbit Anti-GluR-1 (phospho Ser863) Polyclonal Antibody,GRIA1, GLUH1, GLUR1, Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1,Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,Glutamate receptor 1

Molekulargewicht: observerd band 102kDa

Gen-ID: 2890

UniProt: P42261

Pathways: PI3K-Akt Signalweg