XPO1 Antikörper (acLys568)

Produktnummer ABIN7212648

Der Kaninchen Polyklonal anti-XPO1 Antikörper wird verwendet zum Nachweis von XPO1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für XPO1 Antikörper (acLys568) (ABIN7212648)

Target: XPO1 (Exportin 1 (XPO1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-XPO1 Antikörper

Bindungsspezifität: acLys568

Verwendungszweck: Rabbit Anti-CRM1 (Acetyl Lys568) Polyclonal Antibody

Spezifität: Acetyl-CRM1 (K568) Polyclonal Antibody detects endogenous levels of CRM1 protein only when non-acetylation at K568.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CRM1 around the acetylation site of K568

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu XPO1

Target: XPO1 (Exportin 1 (XPO1))

Andere Bezeichnung: CRM1

Hintergrund: XPO1, CRM1, Exportin-1, Exp1, Chromosome region maintenance 1 protein homologThis cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. Exportin 1 also regulates NFAT and AP-1.

Molekulargewicht: 125kD

Gen-ID: 7514

UniProt: O14980

Pathways: M Phase