XPO1 Antikörper (acLys568)

Produktnummer ABIN7212648

Der Kaninchen Polyklonal Anti-XPO1 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, XPO1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für XPO1 Antikörper (acLys568) (ABIN7212648)

Target: XPO1 (Exportin 1 (XPO1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser XPO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-XPO1 Antikörper

Bindungsspezifität: acLys568

Verwendungszweck: CRM1 (Acetyl Lys568) Polyclonal Antibody

Spezifität: Acetyl-CRM1 (K568) Polyclonal Antibody detects endogenous levels of CRM1 protein only when non-acetylation at K568.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CRM1 around the acetylation site of K568

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu XPO1

Target: XPO1 (Exportin 1 (XPO1))

Andere Bezeichnung: CRM1

Hintergrund: Rabbit Anti-CRM1 (Acetyl Lys568) Polyclonal Antibody,XPO1, CRM1, Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog,This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. Exportin 1 also regulates NFAT and AP-1.,Exportin-1

Molekulargewicht: observerd band 125kDa

Gen-ID: 7514

UniProt: O14980

Pathways: M Phase