ESRRA Antikörper (AA 160-240)

Produktnummer ABIN7228432

Dieser Anti-ESRRA Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ESRRA in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für ESRRA Antikörper (AA 160-240) (ABIN7228432)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ESRRA Antikörper

Bindungsspezifität: AA 160-240

Verwendungszweck: ERR1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of ERR1 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ERR1 protein at AA range: 160-240

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: ERR1

Hintergrund: Rabbit Anti-ERR1 Polyclonal Antibody,Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, ERR-alpha, Nuclear receptor subfamily 3 group B member 1,The protein encoded by ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for ESRRA.,ERR1

Molekulargewicht: observerd band 46kDa

Gen-ID: 2101

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha