ESRRA Antikörper (Internal Region)

Produktnummer ABIN6261609

Produktdetails anti-ESRRA Antikörper

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: ESRRA Antibody detects endogenous levels of total ESRRA.

Homologie: Bovine,Horse,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ESRRA, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: ESRRA (ESRRA Produkte)

Synonyme: err1 antikoerper, erra antikoerper, esrral antikoerper, erralpha antikoerper, nr3b1 antikoerper, MGC80854 antikoerper, ESRRA antikoerper, esrl1 antikoerper, LOC100125507 antikoerper, ERRalpha antikoerper, Err1 antikoerper, Estrra antikoerper, Nr3b1 antikoerper, Errra antikoerper, ERR1 antikoerper, ERRa antikoerper, ESRL1 antikoerper, NR3B1 antikoerper, ESTRRA antikoerper, estrogen-related receptor alpha antikoerper, estrogen related receptor alpha L homeolog antikoerper, estrogen related receptor alpha antikoerper, catsper channel auxiliary subunit zeta antikoerper, estrogen related receptor, alpha antikoerper, esrra antikoerper, esrra.L antikoerper, ESRRA antikoerper, LOC100125507 antikoerper, CATSPERZ antikoerper, Esrra antikoerper

Hintergrund:

Description: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.

Gene: ESRRA

Molekulargewicht: ?55 kDa

Gen-ID: 2101

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha