DOT1L Antikörper (AA 700-780)

Produktnummer ABIN7228274

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DOT1L in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DOT1L Antikörper (AA 700-780) (ABIN7228274)

Target: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOT1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DOT1L Antikörper

Bindungsspezifität: AA 700-780

Verwendungszweck: Rabbit Anti-DOT1L Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of DOT1L protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DOT1L protein at AA range: 700-780

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DOT1L

Target: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Andere Bezeichnung: DOT1L

Hintergrund: Histone-lysine N-methyltransferase, H3 lysine-79 specific, DOT1-like protein, Histone H3-K79 methyltransferase, H3-K79-HMTase, Lysine N-methyltransferase 4DOT1L encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. DOT1L (DOT1 Like Histone Lysine Methyltransferase) is a Protein Coding gene. Diseases associated with DOT1L include Diffuse Gastric Cancer and Leukemia, Acute Myeloid. Among its related pathways are Chromatin organization and Transcriptional misregulation in cancer.

Molekulargewicht: 191kD

Gen-ID: 84444

UniProt: Q8TEK3