RAD51C Antikörper (AA 130-210)

Produktnummer ABIN7216750

Dieser Anti-RAD51C Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von RAD51C in WB, ELISA, IF und IHC (p). Geeignet für Human und Affe.

Kurzübersicht für RAD51C Antikörper (AA 130-210) (ABIN7216750)

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RAD51C Antikörper

Bindungsspezifität: AA 130-210

Verwendungszweck: Rad51C Polyclonal Antibody

Spezifität: Rad51C Polyclonal Antibody detects endogenous levels of Rad51C protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Rad51C at AA range: 130-210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Andere Bezeichnung: Rad51C

Hintergrund: Rabbit Anti-Rad51C Polyclonal Antibody,RAD51C, RAD51L2, DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2,RAD51C is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. RAD51 paralog C can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in RAD51C are associated with Fanconi anemia-like syndrome. RAD51C is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.,DNA repair protein RAD51 homolog 3

Molekulargewicht: observerd band 50kDa

Gen-ID: 5889

UniProt: O43502

Pathways: DNA Reparatur