CUBN Antikörper (N-Term)

Produktnummer ABIN7225140

Der Kaninchen Polyklonal anti-CUBN Antikörper wird verwendet zum Nachweis von CUBN in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für CUBN Antikörper (N-Term) (ABIN7225140)

Target: CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CUBN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-CUBN Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Rabbit Anti-Cubilin Polyclonal Antibody

Spezifität: Cubilin Polyclonal Antibody detects endogenous levels of Cubilin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Cubilin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CUBN

Target: CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))

Andere Bezeichnung: Cubilin

Hintergrund: CUBN, IFCR, Cubilin, 460 kDa receptor, Intestinal intrinsic factor receptor, Intrinsic factor-cobalamin receptor, Intrinsic factor-vitamin B12 receptorCubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia.

Molekulargewicht: 400kD

Gen-ID: 8029

UniProt: O60494

Pathways: Metabolism of Steroid Hormones and Vitamin D, Lipid Metabolism