Choline Acetyltransferase Antikörper (Internal Region)

Produktnummer ABIN7214194

Der Kaninchen Polyklonal anti-Choline Acetyltransferase Antikörper wird verwendet zum Nachweis von Choline Acetyltransferase in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für Choline Acetyltransferase Antikörper (Internal Region) (ABIN7214194)

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Choline Acetyltransferase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Choline Acetyltransferase Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-Choactase Polyclonal Antibody

Spezifität: Choactase Polyclonal Antibody detects endogenous levels of Choactase protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Choactase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Choline Acetyltransferase

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Andere Bezeichnung: Choactase

Hintergrund: CHAT, Choline O-acetyltransferase, CHOACTase, ChAT, Choline acetylaseCHAT encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. CHAT product (choline O-acetyltransferase) is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in CHAT have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in CHAT are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for CHAT, and some of these variants have been shown to encode more than one isoform.

Molekulargewicht: 82,70kD

Gen-ID: 1103

UniProt: P28329

Pathways: Skeletal Muscle Fiber Development