CD70 Antikörper (AA 150-193)

Produktnummer ABIN7227764

Der Kaninchen Polyklonal anti-CD70 Antikörper wird verwendet zum Nachweis von CD70 in Proben von Human und Maus. Er wurde validiert für ELISA, IHC und IF.

Kurzübersicht für CD70 Antikörper (AA 150-193) (ABIN7227764)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CD70 Antikörper

Bindungsspezifität: AA 150-193

Verwendungszweck: Rabbit Anti-CD70 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CD70

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CD70 protein at AA range: 150-193

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund: CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD antigen CD70The protein encoded by CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Akt Signaling. is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Akt Signaling.

Gen-ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints