CA8 Antikörper (Internal Region)

Produktnummer ABIN7225002

Dieser Anti-CA8 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CA8 in ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für CA8 Antikörper (Internal Region) (ABIN7225002)

Target: CA8 (Carbonic Anhydrase VIII (CA8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CA8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CA8 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: CA VIII Polyclonal Antibody

Spezifität: CA VIII Polyclonal Antibody detects endogenous levels of CA VIII protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CA VIII

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CA8

Target: CA8 (Carbonic Anhydrase VIII (CA8))

Andere Bezeichnung: CA VIII

Hintergrund: Rabbit Anti-CA VIII Polyclonal Antibody,CA8, CALS, Carbonic anhydrase-related protein, CARP, Carbonic anhydrase VIII, CA-VIII,The protein encoded by CA8 (carbonic anhydrase 8) was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e. The reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in CA8 are associated with osteoporosis, and overexpression of CA8 in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants.,Carbonic anhydrase-related protein

Gen-ID: 767

UniProt: P35219