BMX Antikörper (pTyr566)

Produktnummer ABIN7224400

Der Kaninchen-Polyklonal Anti-BMX-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet zum Nachweis von BMX in Proben aus Human und Maus. }

Kurzübersicht für BMX Antikörper (pTyr566) (ABIN7224400)

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BMX Antikörper

Bindungsspezifität: pTyr566

Verwendungszweck: Bmx (phospho Tyr566) Polyclonal Antibody

Spezifität: Phospho-Bmx (Y566) Polyclonal Antibody detects endogenous levels of Bmx protein only when phosphorylated at Y566.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Bmx Phospho-Tyr566

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu BMX

Target: BMX (BMX Non-Receptor Tyrosine Kinase (BMX))

Andere Bezeichnung: Bmx

Hintergrund: Rabbit Anti-Bmx (phospho Tyr566) Polyclonal Antibody,BMX, Cytoplasmic tyrosine-protein kinase BMX, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase, ETK, NTK38,BMX (BMX non-receptor tyrosine kinase) encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for BMX.,Cytoplasmic tyrosine-protein kinase BMX

Molekulargewicht: observerd band 78kDa

Gen-ID: 660

UniProt: P51813