BLM Antikörper

Produktnummer ABIN7224220

Der Kaninchen Polyklonal anti-BLM Antikörper (ABIN7224220) detektiert spezifisch BLM in ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für BLM Antikörper (ABIN7224220)

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BLM Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-BLM Antikörper

Verwendungszweck: Rabbit Anti-BLM Polyclonal Antibody

Spezifität: BLM Polyclonal Antibody detects endogenous levels of BLM protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human BLM around the non-phosphorylation site of T99

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu BLM

Target: BLM (Bloom Syndrome RecQ Like Helicase (BLM))

Andere Bezeichnung: BLM

Hintergrund: BLM, RECQ2, RECQL3, Bloom syndrome protein, DNA helicase, RecQ-like type 2, RecQ2, RecQ protein-like 3The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.

Gen-ID: 641

UniProt: P54132

Pathways: DNA Reparatur