BLM
Reaktivität: Human
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 488
Applikationshinweise
IP,6 μL/mg lysate,WB,11,000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1000 μg/mL
Buffer
Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
2 - 8 °C
Haltbarkeit
12 months
Target
BLM
(Bloom Syndrome RecQ Like Helicase (BLM))
Andere Bezeichnung
BLM
Hintergrund
Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.