BNIP3 Antikörper (Internal Region)

Produktnummer ABIN7217856

Der Kaninchen Polyklonal anti-BNIP3 Antikörper (ABIN7217856) detektiert spezifisch BNIP3 in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für BNIP3 Antikörper (Internal Region) (ABIN7217856)

Target: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BNIP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-BNIP3 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-BNIP-3 Polyclonal Antibody

Spezifität: BNIP-3 Polyclonal Antibody detects endogenous levels of BNIP-3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human BNIP-3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu BNIP3

Target: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Andere Bezeichnung: BNIP-3

Hintergrund: BNIP3, NIP3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3BNIP3 is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The BCL2 interacting protein 3 interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.

Molekulargewicht: 22kD

Gen-ID: 664

UniProt: Q12983

Pathways: Autophagie, Brown Fat Cell Differentiation