BNIP3 Antikörper (AA 1-164)

Produktnummer ABIN6137620

Produktdetails anti-BNIP3 Antikörper

Target: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Bindungsspezifität: AA 1-164

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BNIP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MGDAAADPPG PALPCEFLRP GCGAPLSPGA QLGRGAPTSA FPPPAAEAHP AARRGLRSPQ LPSGAMSQNG APGMQEESLQ GSWVELHFSN NGNGGSVPAS VSIYNGDMEK ILLDAQHESG RSSSKSSHCD SPPRSQTPQD TNRASETDTH SIGEKNSSQS EEDD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-164 of human BNIP3 (NP_004043.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-BNIP3 Antikörper (ABIN6137620)

Chen, Li, Li, Feng, Liu, Wang, Dai, Xia, Lu, Zhou, Guo: "15-Deoxy-Δ12,14-prostaglandin J2 alleviates hepatic ischemia-reperfusion injury in mice via inducing antioxidant response and inhibiting apoptosis and autophagy." in: Acta pharmacologica Sinica, Vol. 38, Issue 5, pp. 672-687, (2018) (PubMed).

Zhang, Liu, Xue, Ma, Liu, Li, Li, Liu: "Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p." in: Frontiers in molecular neuroscience, Vol. 11, pp. 92, (2018) (PubMed).

Details zu BNIP3

Target: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Andere Bezeichnung: BNIP3 (BNIP3 Produkte)

Synonyme: NIP3 antikoerper, Nip3 antikoerper, BCL2 interacting protein 3 antikoerper, BCL2/adenovirus E1B interacting protein 3 antikoerper, BNIP3 antikoerper, Bnip3 antikoerper

Hintergrund: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.,BNIP3,NIP3,Cancer,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Cardiovascular,Hypoxia,Heart,Mitochondrial Control of Autophagy,BNIP3

Molekulargewicht: 27 kDa

Gen-ID: 664

UniProt: Q12983

Pathways: Autophagie, Brown Fat Cell Differentiation