Acetyl-CoA Carboxylase alpha Antikörper (pSer80)

Produktnummer ABIN7221492

Dieser Anti-Acetyl-CoA Carboxylase alpha-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von Acetyl-CoA Carboxylase alpha in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für Acetyl-CoA Carboxylase alpha Antikörper (pSer80) (ABIN7221492)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Acetyl-CoA Carboxylase alpha Antikörper

Bindungsspezifität: pSer80

Verwendungszweck: ACCα (phospho Ser80) Polyclonal Antibody

Spezifität: Phospho-ACCα (S80) Polyclonal Antibody detects endogenous levels of ACCα protein only when phosphorylated at S80.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human ACCalpha Phospho-Ser80

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Andere Bezeichnung: ACCalpha

Hintergrund: Rabbit Anti-ACCα (phospho Ser80) Polyclonal Antibody,ACACA, ACAC, ACC1, ACCA, Acetyl-CoA carboxylase 1, ACC1, ACC-alpha,Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for ACACA.,Acetyl-CoA carboxylase 1

Gen-ID: 31

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effekt